Richard Bucala, MD, PhD
Dr. Bucala is Professor of Medicine, Pathology, and Epidemiology and Public Health at Yale University. His long-standing research interest has been on the mechanisms by which the immune response produces disease. He is recognized for two research accomplishments: the immune cytokine, MIF (macrophage migration inhibitory factor), and the circulating fibrocyte. While MIF was first identified in the 1930s, it eluded molecular description until the unambiguous cloning of the gene in 1993. Dr. Bucala also was the first to identify the circulating fibrocyte, which mediates fibrosis in different diseases. Within aging, Dr. Bucala recently defined a genetic basis for ischemic damage in the heart and he is an investigator for an NIH biodefense program on the molecular basis of immune dysfunction in the aged.
Dr. Bucala received his BS and MS in Molecular Biophysics and Biochemistry from Yale University, and then a combined MD/PhD at Rockefeller University and Cornell Medical College. After post-doctoral work in Molecular Biology at the Pasteur Institute in Paris, Dr. Bucala trained in Internal Medicine at the Brigham and Women’s Hospital and Harvard Medical School. He underwent sub-specialty training in Rheumatology and was appointed to Assistant Professor at Rockefeller University in 1991. Dr. Bucala was recruited to Yale in 2002 after having served as scientific director of the Picower Institute for Medical Research.
Brookdale Fellow Class of 1988